Time flies ……

N- Alkylated pi systems

I’m a bit over halfway through my summer research period, and I’m pretty impressed with how quickly the time has passed. I guess 10 weeks isn’t quite as long as I first thought! The synthetic portion of my project has moved forward very quickly – and grown quite a bit since the start of the summer. […]

Concise Synthesis and Biological Testing of Natural Products with Potential Anticancer Activity

Quinones are oxidation products of aromatic compounds. Quinones and derivatives thereof are known to show inhibitory properties in the mitochondrial complex I in the mammalian respiratory system. They bind to the active site and inhibit the enzymatic behavior of the mitochondrial complex I. Because complex I is linked to cancer survival, inhibition thereof has been […]

GFP sensors 2: Resistance is centri-futile

IMG_3469

For these past two weeks, I have been growing bacteria to express fluorescent protein so I can harvest it. The protein expression process takes about one week, and I am making four different variants for my experiments. Fortunately, they can be expressed simultaneously. Unfortunately, some of the bacteria cultures have been refusing to grow for some reason. This has […]